The role of HIF prolyl hydroxylases in tumour growth
Tumour hypoxia is a well-known microenvironmental factor that causes cancer progression and resistance to cancer treatment. This involves multiple mechanisms of which the best-understood ones are mediated through transcriptional gene activation by the hypoxia-inducible factors (HIFs). HIFs in turn a...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823110/ |