Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-κB target genes in human breast cancer

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-κB target genes in human breast cancer

NF-κB has been linked to doxorubicin resistance in breast cancer patients. NF-κB nuclear translocation and DNA binding in doxorubicin treated-breast cancer cells have been extensively examined; however its functional relevance at transcriptional level on NF-κB -dependent genes and the biological con...

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Bibliographic Details
Main Authors: Dalmases, Alba, González, Irene, Menendez, Silvia, Arpí, Oriol, Corominas, Josep Maria, Servitja, Sonia, Tusquets, Ignasi, Chamizo, Cristina, Rincón, Raúl, Espinosa, Lluis, Bigas, Anna, Eroles, Pilar, Furriol, Jessica, Lluch, Anna, Rovira, Ana, Albanell, Joan, Rojo, Federico
Format: Online
Language:English
Published: Impact Journals LLC 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960201/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960201/

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