The Anticoagulant Effect of PGI2S and tPA in Transgenic Umbilical Vein Endothelial Cells Is Linked to Up-Regulation of PKA and PKC

The selection of vascular grafts for coronary artery bypass surgery is crucial for a positive outcome. This study aimed to establish a novel line of vascular endothelial cells with a potent anticoagulant effect. A lentiviral vector was used to stably transfect human umbilical vein endothelial cells...

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Bibliographic Details
Main Authors: Wang, Jian-Hua, Yuan, Lin-Jing, Zhong, Zhi-Min, Wen, Zhe-Sheng, Deng, Jian-Ming, Liang, Rong-Xin, Zheng, Min
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958884/