Transcription-coupled mutagenesis by the DNA deaminase AID
Evidence now shows that activation-induced deaminase (AID), wich is involved in switch recombination and somatic hypermutation, travels with RNA polymerase II to deaminate actively transcribed DNA.
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395756/ |