Transcription-coupled mutagenesis by the DNA deaminase AID

Evidence now shows that activation-induced deaminase (AID), wich is involved in switch recombination and somatic hypermutation, travels with RNA polymerase II to deaminate actively transcribed DNA.

Bibliographic Details
Main Authors: Larson, Erik D, Maizels, Nancy
Format: Online
Language:English
Published: BioMed Central 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395756/