The Role of Inflammation Resolution Speed in Airway Smooth Muscle Mass Accumulation in Asthma: Insight from a Theoretical Model

Despite a large amount of in vitro data, the dynamics of airway smooth muscle (ASM) mass increase in the airways of patients with asthma is not well understood. Here, we present a novel mathematical model that describes qualitatively the growth dynamics of ASM cells over short and long terms in the...

Full description

Bibliographic Details
Main Authors: Chernyavsky, Igor L., Croisier, Huguette, Chapman, Lloyd A. C., Kimpton, Laura S., Hiorns, Jonathan E., Brook, Bindi S., Jensen, Oliver E., Billington, Charlotte K., Hall, Ian P., Johnson, Simon R.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954558/