A theoretical model of inflammation- and mechanotransduction- driven asthmatic airway remodelling

Inflammation, airway hyper-responsiveness and airway remodelling are well-established hallmarks of asthma, but their inter-relationships remain elusive. In order to obtain a better understanding of their inter-dependence, we develop a mechanochemical morphoelastic model of the airway wall accounting...

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Bibliographic Details
Main Authors: Hill, Michael, Philp, Christopher J., Billington, Charlotte K., Tatler, Amanda L., Johnson, Simon R., O'Dea, Reuben D., Brook, Bindi S.
Format: Article
Language:English
Published: Springer Verlag 2018
Online Access:http://eprints.nottingham.ac.uk/52504/
http://eprints.nottingham.ac.uk/52504/
http://eprints.nottingham.ac.uk/52504/
http://eprints.nottingham.ac.uk/52504/9/Hill2018_Article_ATheoreticalModelOfInflammatio.pdf