Specific Non-Local Interactions Are Not Necessary for Recovering Native Protein Dynamics

The elastic network model (ENM) is a widely used method to study native protein dynamics by normal mode analysis (NMA). In ENM we need information about all pairwise distances, and the distance between contacting atoms is restrained to the native value. Therefore ENM requires O(N2) information to re...

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Bibliographic Details
Main Authors: Dasgupta, Bhaskar, Kasahara, Kota, Kamiya, Narutoshi, Nakamura, Haruki, Kinjo, Akira R.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953337/