Causal inference of gene regulation with subnetwork assembly from genetical genomics data

Causal inference of gene regulation with subnetwork assembly from genetical genomics data

Deciphering the causal networks of gene interactions is critical for identifying disease pathways and disease-causing genes. We introduce a method to reconstruct causal networks based on exploring phenotype-specific modules in the human interactome and including the expression quantitative trait loc...

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Bibliographic Details
Main Authors: Peng, Chien-Hua, Jiang, Yi-Zhi, Tai, An-Shun, Liu, Chun-Bin, Peng, Shih-Chi, Liao, Chun-Ta, Yen, Tzu-Chen, Hsieh, Wen-Ping
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950678/

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