Causal inference of gene regulation with subnetwork assembly from genetical genomics data

Deciphering the causal networks of gene interactions is critical for identifying disease pathways and disease-causing genes. We introduce a method to reconstruct causal networks based on exploring phenotype-specific modules in the human interactome and including the expression quantitative trait loc...

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Bibliographic Details
Main Authors: Peng, Chien-Hua, Jiang, Yi-Zhi, Tai, An-Shun, Liu, Chun-Bin, Peng, Shih-Chi, Liao, Chun-Ta, Yen, Tzu-Chen, Hsieh, Wen-Ping
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950678/