Systems Biology-Based Identification of Mycobacterium tuberculosis Persistence Genes in Mouse Lungs
Identifying Mycobacterium tuberculosis persistence genes is important for developing novel drugs to shorten the duration of tuberculosis (TB) treatment. We developed computational algorithms that predict M. tuberculosis genes required for long-term survival in mouse lungs. As the input, we used high...
Main Authors: | Dutta, Noton K., Bandyopadhyay, Nirmalya, Veeramani, Balaji, Lamichhane, Gyanu, Karakousis, Petros C., Bader, Joel S. |
---|---|
Format: | Online |
Language: | English |
Published: |
American Society of Microbiology
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944818/ |
Similar Items
-
Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in Mycobacterium tuberculosis
by: Chuang, Yu-Min, et al.
Published: (2015) -
Can the duration of tuberculosis treatment be shortened with higher dosages of rifampicin?
by: Dutta, Noton K., et al.
Published: (2015) -
Mycobacterium Tuberculosis Response to Stress from Reactive Oxygen and Nitrogen Species
by: Lamichhane, Gyanu
Published: (2011) -
Dormancy Phenotype Displayed by Extracellular Mycobacterium tuberculosis within Artificial Granulomas in Mice
by: Karakousis, Petros C., et al.
Published: (2004) -
Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits
by: Subbian, Selvakumar, et al.
Published: (2013)