Systems Biology-Based Identification of Mycobacterium tuberculosis Persistence Genes in Mouse Lungs

Identifying Mycobacterium tuberculosis persistence genes is important for developing novel drugs to shorten the duration of tuberculosis (TB) treatment. We developed computational algorithms that predict M. tuberculosis genes required for long-term survival in mouse lungs. As the input, we used high...

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Bibliographic Details
Main Authors: Dutta, Noton K., Bandyopadhyay, Nirmalya, Veeramani, Balaji, Lamichhane, Gyanu, Karakousis, Petros C., Bader, Joel S.
Format: Online
Language:English
Published: American Society of Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944818/