The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance

Glioblastoma remains one of the most lethal types of cancer, and is the most common brain tumour in adults. In particular, tumour recurrence after surgical resection and radiation invariably occurs regardless of aggressive chemotherapy. Here, we provide evidence that the transcription factor ZEB1 (z...

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Bibliographic Details
Main Authors: Siebzehnrubl, Florian A, Silver, Daniel J, Tugertimur, Bugra, Deleyrolle, Loic P, Siebzehnrubl, Dorit, Sarkisian, Matthew R, Devers, Kelly G, Yachnis, Antony T, Kupper, Marius D, Neal, Daniel, Nabilsi, Nancy H, Kladde, Michael P, Suslov, Oleg, Brabletz, Simone, Brabletz, Thomas, Reynolds, Brent A, Steindler, Dennis A
Format: Online
Language:English
Published: Blackwell Science Inc 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944461/

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