Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

Schwann cell development and peripheral nerve myelination require the serial expression of transcriptional activators, such as Sox10, Oct6/Scip/Pou3f1 and Egr2/Krox20. Here we show that also transcriptional repression, mediated by the zinc-finger protein Zeb2, is essential for differentiation and my...

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Bibliographic Details
Main Authors: Quintes, Susanne, Brinkmann, Bastian G, Ebert, Madlen, Fröb, Franziska, Kungl, Theresa, Arlt, Friederike A, Tarabykin, Victor, Huylebroeck, Danny, Meijer, Dies, Suter, Ueli, Wegner, Michael, Sereda, Michael W, Nave, Klaus-Armin
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964942/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964942/

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