Building Bridges toward Invasion: Tumor Promoter Treatment Induces a Novel Protein Kinase C-Dependent Phenotype in MCF10A Mammary Cell Acini

The potent tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) alters many cellular processes through activation of its receptor protein kinase C (PKC), including gene expression, cell cycle, and the regulation of cell morphology, raising an important question for developing targeted methods t...

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Bibliographic Details
Main Authors: Klos, Kristine S., Warmka, Janel K., Drachenberg, Disa M., Chang, Liang, Luxton, G. W. Gant, Leung, Cheuk T., Schwertfeger, Kathryn L., Wattenberg, Elizabeth V.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944432/