MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis

MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis

Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degrad...

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Main Authors: Hoss, Andrew G., Kartha, Vinay K., Dong, Xianjun, Latourelle, Jeanne C., Dumitriu, Alexandra, Hadzi, Tiffany C., MacDonald, Marcy E., Gusella, James F., Akbarian, Schahram, Chen, Jiang-Fan, Weng, Zhiping, Myers, Richard H.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937267/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937267/

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