The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor

by Takano, Hiroki, Gusella, James F
Published 2002

Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation

by Wang, Jin, Gines, Silvia, MacDonald, Marcy E, Gusella, James F
Published 2005

Genetic analysis of the GRIK2 modifier effect in Huntington's disease

by Zeng, Wenqi, Gillis, Tammy, Hakky, Michael, Djoussé, Luc, Myers, Richard H, MacDonald, Marcy E, Gusella, James F
Published 2006

Unbiased Gene Expression Analysis Implicates the huntingtin Polyglutamine Tract in Extra-mitochondrial Energy Metabolism

by Lee, Jong-Min, Ivanova, Elena V, Seong, Ihn Sik, Cashorali, Tanya, Kohane, Isaac, Gusella, James F, MacDonald, Marcy E
Published 2007

Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum

by Myre, Michael A., Lumsden, Amanda L., Thompson, Morgan N., Wasco, Wilma, MacDonald, Marcy E., Gusella, James F.
Published 2011

Correction: dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism

by Wakabayashi-Ito, Noriko, Doherty, Olugbenga M., Moriyama, Hideaki, Breakefield, Xandra O., Gusella, James F., O'Donnell, Janis M., Ito, Naoto
Published 2011

dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism

by Wakabayashi-Ito, Noriko, Doherty, Olugbenga M., Moriyama, Hideaki, Breakefield, Xandra O., Gusella, James F., O'Donnell, Janis M., Ito, Naoto
Published 2011

Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder

by Bahl, Samira, Chiang, Colby, Beauchamp, Roberta L, Neale, Benjamin M, Daly, Mark J, Gusella, James F, Talkowski, Michael E, Ramesh, Vijaya
Published 2013

HD CAGnome: A Search Tool for Huntingtin CAG Repeat Length-Correlated Genes

by Galkina, Ekaterina I., Shin, Aram, Coser, Kathryn R., Shioda, Toshi, Kohane, Isaac S., Seong, Ihn Sik, Wheeler, Vanessa C., Gusella, James F., MacDonald, Marcy E., Lee, Jong-Min
Published 2014

Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency

by Li, Lin, Walsh, Ryan M., Wagh, Vilas, James, Marianne F., Beauchamp, Roberta L., Chang, Yuh-Shin, Gusella, James F., Hochedlinger, Konrad, Ramesh, Vijaya
Published 2015

Copy Number Variation in Familial Parkinson Disease

by Pankratz, Nathan, Dumitriu, Alexandra, Hetrick, Kurt N., Sun, Mei, Latourelle, Jeanne C., Wilk, Jemma B., Halter, Cheryl, Doheny, Kimberly F., Gusella, James F., Nichols, William C., Myers, Richard H., Foroud, Tatiana, DeStefano, Anita L.
Published 2011

KCTD13 is a major driver of mirrored neuroanatomical phenotypes associated with the 16p11.2 CNV

by Golzio, Christelle, Willer, Jason, Talkowski, Michael E, Oh, Edwin C, Taniguchi, Yu, Jacquemont, Sébastien, Reymond, Alexandre, Sun, Mei, Sawa, Akira, Gusella, James F, Kamiya, Atsushi, Beckmann, Jacques S, Katsanis, Nicholas
Published 2012

Detection of Copy Number Variants Reveals Association of Cilia Genes with Neural Tube Defects

by Chen, Xiaoli, Shen, Yiping, Gao, Yonghui, Zhao, Huizhi, Sheng, Xiaoming, Zou, Jizhen, Lip, Va, Xie, Hua, Guo, Jin, Shao, Hong, Bao, Yihua, Shen, Jianliang, Niu, Bo, Gusella, James F., Wu, Bai-Lin, Zhang, Ting
Published 2013

MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis

by Hoss, Andrew G., Kartha, Vinay K., Dong, Xianjun, Latourelle, Jeanne C., Dumitriu, Alexandra, Hadzi, Tiffany C., MacDonald, Marcy E., Gusella, James F., Akbarian, Schahram, Chen, Jiang-Fan, Weng, Zhiping, Myers, Richard H.
Published 2014

Haplotype analysis of the 4p16.3 region in Portuguese families with Huntington's disease

by Ramos, Eliana Marisa, Gillis, Tammy, Mysore, Jayalakshmi S., Lee, Jong‐Min, Gögele, Martin, D'Elia, Yuri, Pichler, Irene, Sequeiros, Jorge, Pramstaller, Peter P., Gusella, James F., MacDonald, Marcy E., Alonso, Isabel
Published 2015

Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR

by Tai, Derek J. C., Ragavendran, Ashok, Manavalan, Poornima, Stortchevoi, Alexei, Seabra, Catarina M., Erdin, Serkan, Collins, Ryan L., Blumenthal, Ian, Chen, Xiaoli, Shen, Yiping, Sahin, Mustafa, Zhang, Chengsheng, Lee, Charles, Gusella, James F., Talkowski, Michael E.
Published 2016

A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas

by Beauchamp, Roberta L., James, Marianne F., DeSouza, Patrick A., Wagh, Vilas, Zhao, Wen-Ning, Jordan, Justin T., Stemmer-Rachamimov, Anat, Plotkin, Scott R., Gusella, James F., Haggarty, Stephen J., Ramesh, Vijaya
Published 2015

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

by Labadorf, Adam, Hoss, Andrew G., Lagomarsino, Valentina, Latourelle, Jeanne C., Hadzi, Tiffany C., Bregu, Joli, MacDonald, Marcy E., Gusella, James F., Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Myers, Richard H.
Published 2015

Metabolic disruption identified in the Huntington’s disease transgenic sheep model

by Handley, Renee. R., Reid, Suzanne J., Patassini, Stefano, Rudiger, Skye R., Obolonkin, Vladimir, McLaughlan, Clive. J., Jacobsen, Jessie C., Gusella, James F., MacDonald, Marcy E., Waldvogel, Henry J., Bawden, C. Simon, Faull, Richard L. M., Snell, Russell G.
Published 2016

miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement

by Hoss, Andrew G, Labadorf, Adam, Latourelle, Jeanne C, Kartha, Vinay K, Hadzi, Tiffany C, Gusella, James F, MacDonald, Marcy E, Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Vonsattel, Jean Paul, Myers, Richard H
Published 2015