Luteoloside Suppresses Proliferation and Metastasis of Hepatocellular Carcinoma Cells by Inhibition of NLRP3 Inflammasome

The inflammasome is a multi-protein complex which when activated regulates caspase-1 activation and IL-1β secretion. Inflammasome activation is mediated by NLR proteins that respond to stimuli. Among NLRs, NLRP3 senses the widest array of stimuli. NLRP3 inflammasome plays an important role in the de...

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Bibliographic Details
Main Authors: Fan, Shao-hua, Wang, Yan-yan, Lu, Jun, Zheng, Yuan-lin, Wu, Dong-mei, Li, Meng-qiu, Hu, Bin, Zhang, Zi-feng, Cheng, Wei, Shan, Qun
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935965/