Icariin Decreases the Expression of APP and BACE-1 and Reduces the β-amyloid Burden in an APP Transgenic Mouse Model of Alzheimer's Disease

Objective: The purpose of this study was to investigate the effects and pharmacological mechanisms of icariin, which is the main component in the traditional Chinese herb Epimedium, on β-amyloid (Aβ) production in an amyloid precursor protein (APP) transgenic (Tg) mouse model of Alzheimer's dis...

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Bibliographic Details
Main Authors: Zhang, Lan, Shen, Cong, Chu, Jin, Zhang, Ruyi, Li, Yali, Li, Lin
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927130/