Cloud-based simulations on Google Exacycle reveal ligand-modulation of GPCR activation pathways

Simulations can provide tremendous insight into atomistic details of biological mechanisms, but micro- to milliseconds timescales are historically only accessible on dedicated supercomputers. We demonstrate that cloud computing is a viable alternative, bringing long-timescale processes within reach...

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Bibliographic Details
Main Authors: Kohlhoff, Kai J., Shukla, Diwakar, Lawrenz, Morgan, Bowman, Gregory R., Konerding, David E., Belov, Dan, Altman, Russ B., Pande, Vijay S.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923464/