Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma

Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cel...

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Main Author: Beatty, Gregory L
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913694/
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spelling pubmed-39136942014-02-05 Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma Beatty, Gregory L Author's View Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cells, eventually leading to tumor regression. Landes Bioscience 2013-12-01 2013-10-22 /pmc/articles/PMC3913694/ /pubmed/24501687 http://dx.doi.org/10.4161/onci.26837 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Beatty, Gregory L
spellingShingle Beatty, Gregory L
Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
author_facet Beatty, Gregory L
author_sort Beatty, Gregory L
title Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_short Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_full Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_fullStr Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_full_unstemmed Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
title_sort macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
description Macrophages are critical proponents of the growth and development of pancreatic ductal adenocarcinoma. However, if properly instructed, macrophages can acquire anti-tumor properties, including the capacity to degrade the fibrous matrix that surrounds neoplastic lesions and to eliminate malignant cells, eventually leading to tumor regression.
publisher Landes Bioscience
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913694/
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