Engineered chimeric antigen receptor-expressing T cells for the treatment of pancreatic ductal adenocarcinoma

Adoptive cell therapy with chimeric antigen receptor (CAR)-engineered T cells is under investigation as an approach to restore productive T cell immunosurveillance in patients with pancreatic ductal adenocarcinoma. Early findings demonstrate safety of this cell-based therapy and the capacity of CAR-...

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Bibliographic Details
Main Author: Beatty, Gregory L
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063135/