Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection
The Chlamydia trachomatis plasmid is a virulence factor. Plasmid copy number, C. trachomatis load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]...
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| Format: | Online |
| Language: | English |
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American Society for Microbiology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911420/ |
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pubmed-3911420 |
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oai_dc |
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pubmed-39114202014-02-13 Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection Last, Anna R. Roberts, Chrissy h. Cassama, Eunice Nabicassa, Meno Molina-Gonzalez, Sandra Burr, Sarah E. Mabey, David C. W. Bailey, Robin L. Holland, Martin J. Chlamydiology and Rickettsiology The Chlamydia trachomatis plasmid is a virulence factor. Plasmid copy number, C. trachomatis load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]) and there were no associations with C. trachomatis load or disease severity. American Society for Microbiology 2014-01 /pmc/articles/PMC3911420/ /pubmed/24197878 http://dx.doi.org/10.1128/JCM.02618-13 Text en Copyright © 2014 Last et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) . |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Last, Anna R. Roberts, Chrissy h. Cassama, Eunice Nabicassa, Meno Molina-Gonzalez, Sandra Burr, Sarah E. Mabey, David C. W. Bailey, Robin L. Holland, Martin J. |
| spellingShingle |
Last, Anna R. Roberts, Chrissy h. Cassama, Eunice Nabicassa, Meno Molina-Gonzalez, Sandra Burr, Sarah E. Mabey, David C. W. Bailey, Robin L. Holland, Martin J. Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection |
| author_facet |
Last, Anna R. Roberts, Chrissy h. Cassama, Eunice Nabicassa, Meno Molina-Gonzalez, Sandra Burr, Sarah E. Mabey, David C. W. Bailey, Robin L. Holland, Martin J. |
| author_sort |
Last, Anna R. |
| title |
Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection |
| title_short |
Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection |
| title_full |
Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection |
| title_fullStr |
Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection |
| title_full_unstemmed |
Plasmid Copy Number and Disease Severity in Naturally Occurring Ocular Chlamydia trachomatis Infection |
| title_sort |
plasmid copy number and disease severity in naturally occurring ocular chlamydia trachomatis infection |
| description |
The Chlamydia trachomatis plasmid is a virulence factor. Plasmid copy number, C. trachomatis load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]) and there were no associations with C. trachomatis load or disease severity. |
| publisher |
American Society for Microbiology |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911420/ |
| _version_ |
1612054066631802880 |