In Vitro Phosphorylation Does not Influence the Aggregation Kinetics of WT α-Synuclein in Contrast to Its Phosphorylation Mutants

In Vitro Phosphorylation Does not Influence the Aggregation Kinetics of WT α-Synuclein in Contrast to Its Phosphorylation Mutants

The aggregation of alpha-synuclein (α-SYN) into fibrils is characteristic for several neurodegenerative diseases, including Parkinson’s disease (PD). Ninety percent of α-SYN deposited in Lewy Bodies, a pathological hallmark of PD, is phosphorylated on serine129. α-SYN can also be phosphorylated on t...

Full description

Bibliographic Details
Main Authors: Schreurs, Sarah, Gerard, Melanie, Derua, Rita, Waelkens, Etienne, Taymans, Jean-Marc, Baekelandt, Veerle, Engelborghs, Yves
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907855/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907855/

Similar Items