TDP-43 Inclusion Bodies Formed in Bacteria Are Structurally Amorphous, Non-Amyloid and Inherently Toxic to Neuroblastoma Cells

TDP-43 Inclusion Bodies Formed in Bacteria Are Structurally Amorphous, Non-Amyloid and Inherently Toxic to Neuroblastoma Cells

Accumulation of ubiquitin-positive, tau- and α-synuclein-negative intracellular inclusions of TDP-43 in the central nervous system represents the major hallmark correlated to amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusions. Such inclusions have...

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Bibliographic Details
Main Authors: Capitini, Claudia, Conti, Simona, Perni, Michele, Guidi, Francesca, Cascella, Roberta, De Poli, Angela, Penco, Amanda, Relini, Annalisa, Cecchi, Cristina, Chiti, Fabrizio
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907574/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907574/

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