Rodent Models of TDP-43 Proteinopathy: Investigating the Mechanisms of TDP-43-Mediated Neurodegeneration

Since the identification of phosphorylated and truncated transactive response DNA-binding protein 43 (TDP-43) as a primary component of ubiquitinated inclusions in amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusions, much effort has been directed to...

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Bibliographic Details
Main Authors: Gendron, Tania F., Petrucelli, Leonard
Format: Online
Language:English
Published: Humana Press Inc 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207125/