Cohesion promotes nucleolar structure and function

Mutations in the cohesin acetyltransferase Eco1 or the cohesin ring compromise nucleolar function in budding yeast. A mutation in Eco1 that is associated with the human disease Roberts syndrome compromises looping interactions at the ribosomal DNA and transcription. Depletion of cohesion in a single...

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Bibliographic Details
Main Authors: Harris, Bethany, Bose, Tania, Lee, Kenneth K., Wang, Fei, Lu, Shuai, Ross, Rhonda Trimble, Zhang, Ying, French, Sarah L., Beyer, Ann L., Slaughter, Brian D., Unruh, Jay R., Gerton, Jennifer L.
Format: Online
Language:English
Published: The American Society for Cell Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907274/