Cohesion promotes nucleolar structure and function
Mutations in the cohesin acetyltransferase Eco1 or the cohesin ring compromise nucleolar function in budding yeast. A mutation in Eco1 that is associated with the human disease Roberts syndrome compromises looping interactions at the ribosomal DNA and transcription. Depletion of cohesion in a single...
Main Authors: | , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907274/ |