HIF-1-Dependent Induction of Jumonji Domain-Containing Protein (JMJD) 3 under Hypoxic Conditions
Jumonji domain-containing proteins (JMJD) catalyze the oxidative demethylation of a methylated lysine residue of histones by using O2, α-ketoglutarate, vitamin C, and Fe(II). Several JMJDs are induced by hypoxic stress to compensate their presumed reduction in catalytic activity under hypoxia. In th...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korea Society for Molecular and Cellular Biology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907005/ |