Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old☆

Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old☆

Inherited genetic variation of mitochondrial DNA (mtDNA) could account for the missing heritability of human longevity and healthy aging. Here, we show no robust association between common genetic variants of mtDNA and frailty (an “unhealthy aging” phenotype) or mortality in 700, more than 85-year-o...

Full description

Bibliographic Details
Main Authors: Collerton, Joanna, Ashok, Deepthi, Martin-Ruiz, Carmen, Pyle, Angela, Hudson, Gavin, Yadegarfar, Mohammad, Davies, Karen, Jagger, Carol, von Zglinicki, Thomas, Kirkwood, Thomas B.L., Chinnery, Patrick F.
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906612/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906612/

Similar Items