Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo
Sodium fluoride (NaF) is associated with embryonic and fetal development abnormalities, but the mechanism by which this occurs is unclear. DNA methylation, an important epigenetic reprogramming mechanism, is essential for normal embryonic development. Thus, we investigated the effect of NaF on DNA m...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Springer Berlin Heidelberg
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906544/ |