Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma

Glioma includes astrocytoma, oligodendroglioma, ependymoma and glioblastoma. We previously reported the epigenetic silencing of paternally expressed gene 3 (PEG3) in glioma cell lines. In this study, we investigated methylation of an exonic CpG island in the promoter region and the expression of PEG...

Full description

Bibliographic Details
Main Authors: Otsuka, Susumu, Maegawa, Shinji, Takamura, Ayumi, Kamitani, Hideki, Watanabe, Takashi, Oshimura, Mitsuo, Nanba, Eiji
Format: Online
Language:English
Published: The Japan Academy 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524298/