Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients
The methylation of O6-methylguanine DNA methyltransferase (MGMT) gene promoter is a key biological marker in clinical neuro-oncology. Nevertheless, there is no consensus concerning the best technique for its assessment. In a recent study comparing five methods to analyze MGMT status, we found that t...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer US
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905192/ |