Clinical Neuropathology practice guide 5-2015: MGMT methylation pyrosequencing in glioblastoma: unresolved issues and open questions

O6-methylguanine-methyltransferase (MGMT) promoter methylation status has prognostic and, in the subpopulation of elderly patients, predictive value in newly diagnosed glioblastoma. Therefore, knowledge of the MGMT promoter methylation status is important for clinical decision-making. So far, MGMT...

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Bibliographic Details
Main Authors: Bienkowski, Michal, Berghoff, Anna S., Marosi, Christine, Wöhrer, Adelheid, Heinzl, Harald, Hainfellner, Johannes A., Preusser, Matthias
Format: Online
Language:English
Published: Dustri-Verlag Dr. Karl Feistle 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542181/