Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes

The aim of the present study was to determine whether the endothelial dysfunction associated with CAD (coronary artery disease) and T2D (Type 2 diabetes mellitus) is concomitant with elevated mtROS (mitochondrial reactive oxygen species) production in the endothelium and establish if this, in turn,...

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Bibliographic Details
Main Authors: Mackenzie, Ruth M., Salt, Ian P., Miller, William H., Logan, Angela, Ibrahim, Hagar A., Degasperi, Andrea, Dymott, Jane A., Hamilton, Carlene A., Murphy, Michael P., Delles, Christian, Dominiczak, Anna F.
Format: Online
Language:English
Published: Portland Press Ltd. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903000/