AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production

Vascular endothelial growth factor (VEGF) is an important regulator of endothelial cell function. VEGF stimulates NO production, proposed to be a result of phosphorylation and activation of endothelial NO synthase (eNOS) at Ser1177. Phosphorylation of eNOS at this site also occurs after activation o...

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Bibliographic Details
Main Authors: Reihill, James A., Ewart, Marie-Ann, Hardie, D. Grahame, Salt, Ian P.
Format: Online
Language:English
Published: Academic Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828119/