DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking

Disrupted-In-Schizophrenia 1 (DISC1) is a candidate risk factor for schizophrenia, bipolar disorder and severe recurrent depression. Here, we demonstrate that DISC1 associates robustly with trafficking-protein-Kinesin-binding-1 which is, in turn, known to interact with the outer mitochondrial membra...

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Bibliographic Details
Main Authors: Ogawa, Fumiaki, Malavasi, Elise L.V., Crummie, Darragh K., Eykelenboom, Jennifer E., Soares, Dinesh C., Mackie, Shaun, Porteous, David J., Millar, J. Kirsty
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900104/