A method for estimating the oxygen consumption rate in multicellular tumour spheroids

Hypoxia occurs when oxygen levels within a tissue drop below normal physiological levels. In tumours, hypoxia is associated with poor prognosis, increased likelihood of metastasis and resistance to therapy. Imaging techniques, for example, positron emission tomography, are increasingly used in the m...

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Bibliographic Details
Main Authors: Grimes, David Robert, Kelly, Catherine, Bloch, Katarzyna, Partridge, Mike
Format: Online
Language:English
Published: The Royal Society 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899881/