Response of EMT6 multicellular tumour spheroids to hyperthermia and cytotoxic drugs.

The response of multicellular tumour spheroids of the EMT6 cell line to combinations of hyperthermia and Bleomycin (BLM) or Adriamycin (ADM) has been investigated. Using this model system, we have demonstrated enhanced BLM cytotoxicity at 43 degrees C and also heat-induced drug tolerance to BLM at 4...

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Bibliographic Details
Main Authors: Morgan, J. E., Bleehen, N. M.
Format: Online
Language:English
Published: 1981
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010598/