Overexpression of IL-10 in C2D Macrophages Promotes a Macrophage Phenotypic Switch in Adipose Tissue Environments

Adipose tissue macrophages are a heterogeneous collection of classically activated (M1) and alternatively activated (M2) macrophages. Interleukin 10 (IL-10) is an anti-inflammatory cytokine, secreted by a variety of cell types including M2 macrophages. We generated a macrophage cell line stably over...

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Bibliographic Details
Main Authors: Xie, Linglin, Fu, Qiang, Ortega, Teresa M., Zhou, Lun, Rasmussen, Dane, O’Keefe, Jacy, Zhang, Ke K., Chapes, Stephen K.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897709/