KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages

Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype. Both glioma and infiltrating M/MΦ cells express the Ca2+-activated K+ channel (K...

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Bibliographic Details
Main Authors: Grimaldi, A, D'Alessandro, G, Golia, M T, Grössinger, E M, Di Angelantonio, S, Ragozzino, D, Santoro, A, Esposito, V, Wulff, H, Catalano, M, Limatola, C
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855657/