Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations
The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4-membered ring system. The scope of the reaction...
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| Format: | Online |
| Language: | English |
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Beilstein-Institut
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896293/ |
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pubmed-3896293 |
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pubmed-38962932014-01-21 Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations Ghashghaei, Ouldouz Manna, Consiglia Annamaria Vicente-García, Esther Revés, Marc Lavilla, Rodolfo Letter The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4-membered ring system. The scope of the reaction regarding the imine and isocyanide ranges has been determined, and also some mechanistic variations and structural features have been described. Beilstein-Institut 2014-01-06 /pmc/articles/PMC3896293/ /pubmed/24454559 http://dx.doi.org/10.3762/bjoc.10.3 Text en Copyright © 2014, Ghashghaei et al; licensee Beilstein-Institut. http://www.beilstein-journals.org/bjoc This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Ghashghaei, Ouldouz Manna, Consiglia Annamaria Vicente-García, Esther Revés, Marc Lavilla, Rodolfo |
| spellingShingle |
Ghashghaei, Ouldouz Manna, Consiglia Annamaria Vicente-García, Esther Revés, Marc Lavilla, Rodolfo Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| author_facet |
Ghashghaei, Ouldouz Manna, Consiglia Annamaria Vicente-García, Esther Revés, Marc Lavilla, Rodolfo |
| author_sort |
Ghashghaei, Ouldouz |
| title |
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| title_short |
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| title_full |
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| title_fullStr |
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| title_full_unstemmed |
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| title_sort |
studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations |
| description |
The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4-membered ring system. The scope of the reaction regarding the imine and isocyanide ranges has been determined, and also some mechanistic variations and structural features have been described. |
| publisher |
Beilstein-Institut |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896293/ |
| _version_ |
1612049025170669568 |