Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics

In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has received much attention. This because they have shown in many cases enhanced pharmacological properties over their natural peptide analogues. In particular, the incorporation of cyclic constructs into peptides is of...

Full description

Bibliographic Details
Main Authors: Koopmanschap, Gijs, Ruijter, Eelco, Orru, Romano VA
Format: Online
Language:English
Published: Beilstein-Institut 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943360/