The thyroid hormone receptor β induces DNA damage and premature senescence

The thyroid hormone receptor β induces DNA damage and premature senescence

Thyroid hormone and its receptor act in concert with NRF1 to increase cellular respiration and reactive oxygen species production, leading to DNA damage and premature senescence in susceptible cells.

Bibliographic Details
Main Authors: Zambrano, Alberto, García-Carpizo, Verónica, Gallardo, María Esther, Villamuera, Raquel, Gómez-Ferrería, Maria Ana, Pascual, Angel, Buisine, Nicolas, Sachs, Laurent M., Garesse, Rafael, Aranda, Ana
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795/
id pubmed-3882795
recordtype oai_dc
spelling pubmed-38827952014-07-06 The thyroid hormone receptor β induces DNA damage and premature senescence Zambrano, Alberto García-Carpizo, Verónica Gallardo, María Esther Villamuera, Raquel Gómez-Ferrería, Maria Ana Pascual, Angel Buisine, Nicolas Sachs, Laurent M. Garesse, Rafael Aranda, Ana Research Articles Thyroid hormone and its receptor act in concert with NRF1 to increase cellular respiration and reactive oxygen species production, leading to DNA damage and premature senescence in susceptible cells. The Rockefeller University Press 2014-01-06 /pmc/articles/PMC3882795/ /pubmed/24395638 http://dx.doi.org/10.1083/jcb.201305084 Text en © 2014 Zambrano et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zambrano, Alberto
García-Carpizo, Verónica
Gallardo, María Esther
Villamuera, Raquel
Gómez-Ferrería, Maria Ana
Pascual, Angel
Buisine, Nicolas
Sachs, Laurent M.
Garesse, Rafael
Aranda, Ana
spellingShingle Zambrano, Alberto
García-Carpizo, Verónica
Gallardo, María Esther
Villamuera, Raquel
Gómez-Ferrería, Maria Ana
Pascual, Angel
Buisine, Nicolas
Sachs, Laurent M.
Garesse, Rafael
Aranda, Ana
The thyroid hormone receptor β induces DNA damage and premature senescence
author_facet Zambrano, Alberto
García-Carpizo, Verónica
Gallardo, María Esther
Villamuera, Raquel
Gómez-Ferrería, Maria Ana
Pascual, Angel
Buisine, Nicolas
Sachs, Laurent M.
Garesse, Rafael
Aranda, Ana
author_sort Zambrano, Alberto
title The thyroid hormone receptor β induces DNA damage and premature senescence
title_short The thyroid hormone receptor β induces DNA damage and premature senescence
title_full The thyroid hormone receptor β induces DNA damage and premature senescence
title_fullStr The thyroid hormone receptor β induces DNA damage and premature senescence
title_full_unstemmed The thyroid hormone receptor β induces DNA damage and premature senescence
title_sort thyroid hormone receptor β induces dna damage and premature senescence
description Thyroid hormone and its receptor act in concert with NRF1 to increase cellular respiration and reactive oxygen species production, leading to DNA damage and premature senescence in susceptible cells.
publisher The Rockefeller University Press
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795/
_version_ 1612044886663495680

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