The thyroid hormone receptor β induces DNA damage and premature senescence

The thyroid hormone receptor β induces DNA damage and premature senescence

Thyroid hormone and its receptor act in concert with NRF1 to increase cellular respiration and reactive oxygen species production, leading to DNA damage and premature senescence in susceptible cells.

Bibliographic Details
Main Authors: Zambrano, Alberto, García-Carpizo, Verónica, Gallardo, María Esther, Villamuera, Raquel, Gómez-Ferrería, Maria Ana, Pascual, Angel, Buisine, Nicolas, Sachs, Laurent M., Garesse, Rafael, Aranda, Ana
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795/

Similar Items