PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

Amyotrophic lateral sclerosis (ALS) is associated with progressive degeneration of motor neurons. Several of the genes associated with this disease encode proteins involved in RNA processing, including fused-in-sarcoma/translocated-in-sarcoma (FUS/TLS). FUS is a member of the heterogeneous nuclear r...

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Bibliographic Details
Main Authors: Rulten, Stuart L., Rotheray, Amy, Green, Ryan L., Grundy, Gabrielle J., Moore, Duncan A. Q., Gómez-Herreros, Fernando, Hafezparast, Majid, Caldecott, Keith W
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874156/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874156/

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