Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses

Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses

The major limitation of the clinical use of replication-incompetent adenovirus (Ad) vectors is the interference by innate immune responses, including induction of inflammatory cytokines and interferons (IFN), following in vivo application of Ad vectors. Ad vector-induced production of inflammatory c...

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Bibliographic Details
Main Authors: Machitani, Mitsuhiro, Yamaguchi, Tomoko, Shimizu, Kahori, Sakurai, Fuminori, Katayama, Kazufumi, Kawabata, Kenji, Mizuguchi, Hiroyuki
Format: Online
Language:English
Published: MDPI 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857070/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857070/

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