TNNI3K is a novel mediator of myofilament function and phosphorylates cardiac troponin I

The phosphorylation of cardiac troponin I (cTnI) plays an important role in the contractile dysfunction associated with heart failure. Human cardiac troponin I-interacting kinase (TNNI3K) is a novel cardiac-specific functional kinase that can bind to cTnI in a yeast two-hybrid screen. The purpose of...

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Bibliographic Details
Main Authors: Wang, Hui, Wang, Lin, Song, Li, Zhang, Yan-Wan, Ye, Jue, Xu, Rui-Xia, Shi, Na, Meng, Xian-Min
Format: Online
Language:English
Published: Associação Brasileira de Divulgação Científica 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854359/