Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness

Titin-based myofilament stiffness is largely modulated by phosphorylation of its elastic I-band regions N2-Bus (decreases passive stiffness, PT) and PEVK (increases PT). Here, we tested the hypothesis that acute exercise changes titin phosphorylation and modifies myofilament stiffness. Adult rats we...

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Bibliographic Details
Main Authors: Müller, Anna E., Kreiner, Matthias, Kötter, Sebastian, Lassak, Philipp, Bloch, Wilhelm, Suhr, Frank, Krüger, Martina
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238368/