Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy – Results of a United Kingdom phase II trial (CNS 2007 04)☆

Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy – Results of a United Kingdom phase II trial (CNS 2007 04)☆

Diffuse intrinsic pontine glioma (DIPG) has a dismal prognosis with no chemotherapy regimen so far resulting in any significant improvement over standard radiotherapy. In this trial, a prolonged regimen (21/28 d) of temozolomide was studied with the aim of overcoming O6-methylguanine methyltransfera...

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Bibliographic Details
Main Authors: Bailey, S., Howman, A., Wheatley, K., Wherton, D., Boota, N., Pizer, B., Fisher, D., Kearns, P., Picton, S., Saran, F., Gibson, M., Glaser, A., Connolly, D.J.A., Hargrave, D.
Format: Online
Language:English
Published: Elsevier Science Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853623/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853623/

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