Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis

Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis

Pancreatic islets adapt to insulin resistance through a complex set of changes, including β-cell hyperplasia and hypertrophy. To determine if islet vascularization changes in response to insulin resistance, we investigated three independent models of insulin resistance: ob/ob, GLUT4+/−, and mice wit...

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Bibliographic Details
Main Authors: Dai, Chunhua, Brissova, Marcela, Reinert, Rachel B., Nyman, Lara, Liu, Eric H., Thompson, Courtney, Shostak, Alena, Shiota, Masakazu, Takahashi, Takamune, Powers, Alvin C.
Format: Online
Language:English
Published: American Diabetes Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837044/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837044/

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