The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

The large Maf transcription factors, MafA and MafB, are expressed with distinct spatial–temporal patterns in rodent islet cells. Analysis of Mafa−/− and pancreas-specific Mafa∆panc deletion mutant mice demonstrated a primary role for MafA in adult β-cell activity, different from the embryonic import...

Full description

Bibliographic Details
Main Authors: Hang, Yan, Yamamoto, Tsunehiko, Benninger, Richard K.P., Brissova, Marcela, Guo, Min, Bush, Will, Piston, David W., Powers, Alvin C., Magnuson, Mark, Thurmond, Debbie C., Stein, Roland
Format: Online
Language:English
Published: American Diabetes Association 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030115/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030115/

Similar Items